Thrombin-derived host defence peptide modulates neutrophil rolling and migration in vitro and functional response in vivo

Thrombin-derived host defence peptide modulates neutrophil rolling and migration in vitro and functional response in vivo

Host defence peptides (HDPs) derived from the C-terminus of thrombin are proteolytically generated by enzymes released during inflammation and wounding. In this work, we studied the effects of the prototypic peptide GKY25 (GKYGFYTHVFRLKKWIQKVIDQFGE), on neutrophil functions. In vitro, GKY25 was show...

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Bibliographic Details
Main Authors: Lim, Chun Hwee, Puthia, Manoj, Butrym, Marta, Tay, Hui Min, Lee, Michelle Zi Yi, Hou, Han Wei, Schmidtchen, Artur
Other Authors: Interdisciplinary Graduate School (IGS)
Format: Article
Language:English
Published: 2017
Subjects:
Neutrophils
Sepsis
Online Access:https://hdl.handle.net/10356/86509
http://hdl.handle.net/10220/44087
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/86509
http://hdl.handle.net/10220/44087

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