Carbene-catalyzed reductive coupling of nitrobenzyl bromide and nitroalkene via the single-electron-transfer (SET) process and formal 1,4-addition

• Main Authors: Wang, Yuhuang, Du, Yu, Huang, Xuan, Wu, Xingxing, Zhang, Yuexia, Yang, Song, Chi, Robin Yonggui
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: Science::Chemistry; Single-Electron-Transfer; Nitrobenzyl Bromide
• Online Access: https://hdl.handle.net/10356/85595; http://hdl.handle.net/10220/43776
• Institution: Nanyang Technological University

A carbene-catalyzed reductive 1,4-addition of nitrobenzyl bromides to nitroalkenes is disclosed. The reaction proceeds via a carbene-enabled single-electron-transfer process that generates radicals as key intermediates. The present study expands the potentials of carbene catalysis and offers unusual...