Detection of proteoglycan loss from articular cartilage using Brillouin microscopy, with applications to osteoarthritis

The degeneration of articular cartilage (AC) occurs in osteoarthritis (OA), which is a leading cause of pain and disability in middle-aged and older people. The early disease-related changes in cartilage extra-cellular matrix (ECM) start with depletion of proteoglycan (PG), leading to an increase in...

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Bibliographic Details
Main Authors: Wu, Pei-Jung, Masouleh, Maryam Imani, Dini, Daniele, Paterson, Carl, Török, Peter, Overby, Darryl R., Kabakova, Irina V.
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/86181
http://hdl.handle.net/10220/49855
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Institution: Nanyang Technological University
Language: English