Detection of proteoglycan loss from articular cartilage using Brillouin microscopy, with applications to osteoarthritis
The degeneration of articular cartilage (AC) occurs in osteoarthritis (OA), which is a leading cause of pain and disability in middle-aged and older people. The early disease-related changes in cartilage extra-cellular matrix (ECM) start with depletion of proteoglycan (PG), leading to an increase in...
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Main Authors: | , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/86181 http://hdl.handle.net/10220/49855 |
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Institution: | Nanyang Technological University |
Language: | English |