Detection of proteoglycan loss from articular cartilage using Brillouin microscopy, with applications to osteoarthritis
The degeneration of articular cartilage (AC) occurs in osteoarthritis (OA), which is a leading cause of pain and disability in middle-aged and older people. The early disease-related changes in cartilage extra-cellular matrix (ECM) start with depletion of proteoglycan (PG), leading to an increase in...
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Main Authors: | , , , , , , |
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格式: | Article |
語言: | English |
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2019
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在線閱讀: | https://hdl.handle.net/10356/86181 http://hdl.handle.net/10220/49855 |
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機構: | Nanyang Technological University |
語言: | English |