LDSplitDB : a database for studies of meiotic recombination hotspots in MHC using human genomic data

• Main Authors: Guo, Jing, Chen, Hao, Yang, Peng, Lee, Yew Ti, Wu, Min, Przytycka, Teresa M., Kwoh, Chee Keong, Zheng, Jie
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: 1000 Genomes Project; MHC
• Online Access: https://hdl.handle.net/10356/86205; http://hdl.handle.net/10220/45252
• Institution: Nanyang Technological University

Background: Meiotic recombination happens during the process of meiosis when chromosomes inherited from two parents exchange genetic materials to generate chromosomes in the gamete cells. The recombination events tend to occur in narrow genomic regions called recombination hotspots. Its dysregulatio...