Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome

• Main Authors: Ertel, Adam, Wang, Guangxue, Gormley, Michael, Qiao, Jing, Zhao, Qian, Wang, Min, Di Sante, Gabriele, Deng, Shengqiong, Dong, Lin, Pestell, Tim, Ju, Xiaoming, Casimiro, Mathew C., Addya, Sankar, Tozeren, Ayden, Li, Qinchuan, Yu, Zuoren, Pestell, Richard George
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Cyclin D1; MiRNA
• Online Access: https://hdl.handle.net/10356/86214; http://hdl.handle.net/10220/45246
• Institution: Nanyang Technological University

Background: Genetic classification of breast cancer based on the coding mRNA suggests the evolution of distinct subtypes. Whether the non-coding genome is altered concordantly with the coding genome and the mechanism by which the cell cycle directly controls the non-coding genome is poorly understoo...