Aptamer adaptive binding assessed by stilbene photoisomerization towards regenerating aptasensors

• Main Authors: Zhou, Yubin, Yuanyuan, Wu, Pokholenko, Oleksandr, Grimsrud, Marissa, Sham, Yuk, Papper, Vladislav, Marks, Robert, Steele, Terry
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2017
• Subjects: Stilbene; Aptamer
• Online Access: https://hdl.handle.net/10356/86262; http://hdl.handle.net/10220/43970
• Institution: Nanyang Technological University

Fluorescent aptasensors are reliant on static fluorescence intensity measurements, which suffer drawbacks such as background interference and laborious separation procedures. A unique aptasensor based on the photochrome aptamer switch assay (PHASA) has been developed that is independent of backgroun...