Rotation of Guanine Amino Groups in G-Quadruplexes: A Probe for Local Structure and Ligand Binding

• المؤلفون الرئيسيون: Adrian, Michael, Winnerdy, Fernaldo Richtia, Heddi, Brahim, Phan, Anh Tuân
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: DNA; Guanine
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/86336; http://hdl.handle.net/10220/44018
• المؤسسة: Nanyang Technological University

Nucleic acids are dynamic molecules whose functions may depend on their conformational fluctuations and local motions. In particular, amino groups are dynamic components of nucleic acids that participate in the formation of various secondary structures such as G-quadruplexes. Here, we present a cost...