Long range recognition and selection in IDPs : the interactions of the C-terminus of p53

The C-terminal domain of p53 is an extensively studied IDP, interacting with different partners through multiple distinct conformations. To explore the interplay between preformed structural elements and intrinsic fluctuations in its folding and binding we combine extensive atomistic equilibrium and...

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Bibliographic Details
Main Authors: Kannan, Srinivasaraghavan, Lane, David P., Verma, Chandra Shekhar
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/86585
http://hdl.handle.net/10220/46690
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Institution: Nanyang Technological University
Language: English