Crystallographic and enzymatic insights into the mechanisms of Mg-ADP inhibition in the A1 complex of the A1AO ATP synthase

F-ATP synthases are described to have mechanisms which regulate the unnecessary depletion of ATP pool during an energy limited state of the cell. Mg-ADP inhibition is one of the regulatory features where Mg-ADP gets entrapped in the catalytic site, preventing the binding of ATP and further inhibitin...

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Bibliographic Details
Main Authors: Singh, Dhirendra, Grüber, Gerhard
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87069
http://hdl.handle.net/10220/44273
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Institution: Nanyang Technological University
Language: English