Lowering Low-Density Lipoprotein Particles in Plasma Using Dextran Sulphate Co-Precipitates Procoagulant Extracellular Vesicles

• Main Authors: Sze, Siu Kwan, van de Weg, Sander M., Vernooij, Flora, Schoneveld, Arjan, Tan, Sock-Hwee, Versteeg, Henri, Timmers, Leo, Lam, Carolyn, Wang, Jiong-Wei, Zhang, Ya-Nan, de Kleijn, Dominique P.V.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Extracellular Vesicles; Lipoprotein Particles
• Online Access: https://hdl.handle.net/10356/87407; http://hdl.handle.net/10220/44401
• Institution: Nanyang Technological University

Plasma extracellular vesicles (EVs) are lipid membrane vesicles involved in several biological processes including coagulation. Both coagulation and lipid metabolism are strongly associated with cardiovascular events. Lowering very-low- and low-density lipoprotein ((V)LDL) particles via dextran sulp...