Combination therapy strategy of quorum quenching enzyme and quorum sensing inhibitor in suppressing multiple quorum sensing pathways of P. Aeruginosa

• المؤلفون الرئيسيون: Fong, July, Zhang, Chaodong, Yang, Renliang, Boo, Zhao Zhi, Tan, Soon Keat, Givskov, Michael, Liu, Xue-Wei, Bin, Wu, Su, Haibin, Yang, Liang, Nielsen, Thomas Eiland
• مؤلفون آخرون: School of Civil and Environmental Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Quorum Sensing Inhibitors (QSI); Quorum Quenching Enzymes (QQE)
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/87495; http://hdl.handle.net/10220/45422

The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence factors and formation of drug-resistant biofilms. Targeti...