A trade-off between solubility enhancement and physical stability upon simultaneous amorphization and nanonization of curcumin in comparison to amorphization alone

A trade-off between solubility enhancement and physical stability upon simultaneous amorphization and nanonization of curcumin in comparison to amorphization alone

The numerous health benefits of curcumin (CUR) have not been fully realized due to its low aqueous solubility, resulting in poor bioavailability. While amorphization of CUR via amorphous solid dispersion (ASD) represents a well-established CUR solubility enhancement strategy, simultaneous amorphizat...

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Bibliographic Details
Main Authors: Wong, Jerome Jie Long, Yu, Hong, Lim, Li Ming, Hadinoto, Kunn
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2018
Subjects:
Curcumin
Nanoparticles
Online Access:https://hdl.handle.net/10356/87714
http://hdl.handle.net/10220/45493
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/87714
http://hdl.handle.net/10220/45493

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