Thrombin and plasmin alter the proteome of neutrophil extracellular traps

• Main Authors: Lim, Chun Hwee, Adav, Sunil Shankar, Sze, Siu Kwan, Choong, Yeu Khai, Saravanan, Rathi, Schmidtchen, Artur
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Neutrophil Extracellular Traps; Proteome
• Online Access: https://hdl.handle.net/10356/87758; http://hdl.handle.net/10220/45538
• Institution: Nanyang Technological University

Neutrophil extracellular traps (NETs) consist of a decondensed DNA scaffold decorated with neutrophil-derived proteins. The proteome of NETs, or “NETome,” has been largely elucidated in vitro. However, components such as plasma and extracellular matrix proteins may affect the NETome under physiologi...