The action of mimetic peptides on connexins protects fibroblasts from the negative effects of ischemia reperfusion

• Main Authors: Glass, Beverley J., Hu, Rebecca G., Phillips, Anthony R. J., Becker, David Lawrence
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Hemichannel; Gap Junction; DRNTU::Science::Medicine
• Online Access: https://hdl.handle.net/10356/87848; http://hdl.handle.net/10220/46847
• Institution: Nanyang Technological University

Connexins have been proposed as a target for therapeutic treatment of a variety of conditions. The main approaches have been by antisense or small peptides specific against connexins. Some of these peptides enhance communication while others interfere with connexin binding partners or bind to the in...