The action of mimetic peptides on connexins protects fibroblasts from the negative effects of ischemia reperfusion

• المؤلفون الرئيسيون: Glass, Beverley J., Hu, Rebecca G., Phillips, Anthony R. J., Becker, David Lawrence
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Hemichannel; Gap Junction; DRNTU::Science::Medicine
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/87848; http://hdl.handle.net/10220/46847
• المؤسسة: Nanyang Technological University

Connexins have been proposed as a target for therapeutic treatment of a variety of conditions. The main approaches have been by antisense or small peptides specific against connexins. Some of these peptides enhance communication while others interfere with connexin binding partners or bind to the in...