Utf1 contributes to intergenerational epigenetic inheritance of pluripotency

Undifferentiated embryonic cell transcription factor 1 (Utf1) is expressed in pluripotent embryonic stem cells (ESCs) and primordial germ cells (PGCs). Utf1 expression is directly controlled by pluripotency factors Oct4 and Sox2, which form a ternary complex with the Utf1 enhancer. The Utf1 protein...

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Bibliographic Details
Main Authors: Bao, Qiuye, Morshedi, Amir, Wang, Fulu, Bhargy, Sharma, Pervushin, Konstantin, Yu, Wei-Ping, Dröge, Peter
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87884
http://hdl.handle.net/10220/45565
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Institution: Nanyang Technological University
Language: English