Integrative analyses of translatome and transcriptome reveal important translational controls in brown and white adipose regulated by microRNAs

• Main Authors: Reid, David W., Xu, Dan, Chen, Peng, Yang, Hongyuan, Sun, Lei
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: DRNTU::Engineering::Bioengineering; White Adipocytes; Transcriptome
• Online Access: https://hdl.handle.net/10356/87975; http://hdl.handle.net/10220/45588
• Institution: Nanyang Technological University

The epidemic of obesity and diabetes has markedly spurred the research interest in adipocyte biology. Brown adipocytes are specialized for energy expenditure and of therapeutic interest for treatment of metabolic diseases, but how brown adipocytes are distinguished from white adipocytes at the level...