De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis

• Main Authors: Ding C., Lim Y.C., Chia S.Y., Walet A.C.E., Xu S., Lo K.A., Zhao Y., Zhu D., Shan Z., Chen Q., Leow M.K.-S., Xu D., Sun L.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: long untranslated RNA; long untranslated RNA dprdm16; messenger RNA; short hairpin RNA; transcriptome; unclassified drug; DNA binding protein; PRDM16 protein, human; transcription factor; assay; correlation; fat; genetic marker; metabolism; muscle; obesity; protein; risk assessment; RNA; adipogenesis; adult; animal cell; animal experiment; animal model; animal tissue; Article; brown adipocyte; brown adipose tissue; cell differentiation; cell maturation; cold exposure; controlled study; exon; gene expression level; gene knockdown; genetic conservation; high throughput sequencing; human; human cell; in vitro study; in vivo study; lipid storage; mouse; nonhuman; open reading frame; RNA sequence; tissue specificity; white adipose tissue; animal; cell culture; cold; conserved sequence; cytology; genetics; growth, development and aging; thermogenesis; tissue distribution; Adipocytes, Brown; Adipogenesis; Adipose Tissue, Brown; Animals; Cell Differentiation; Cells, Cultured; Cold Temperature; Conserved Sequence; DNA-Binding Proteins; Gene Knockdown Techniques; Genetic Markers; Humans; Mice; Obesity; RNA, Long Noncoding; Thermogenesis; Tissue Distribution; Transcription Factors; Transcriptome
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174232
• Institution: National University of Singapore

10.1038/s41467-018-03754-3