De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis

10.1038/s41467-018-03754-3

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Main Authors:	Ding C., Lim Y.C., Chia S.Y., Walet A.C.E., Xu S., Lo K.A., Zhao Y., Zhu D., Shan Z., Chen Q., Leow M.K.-S., Xu D., Sun L.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	long untranslated RNA long untranslated RNA dprdm16 messenger RNA short hairpin RNA transcriptome unclassified drug DNA binding protein PRDM16 protein, human transcription factor assay correlation fat genetic marker metabolism muscle obesity protein risk assessment RNA adipogenesis adult animal cell animal experiment animal model animal tissue Article brown adipocyte brown adipose tissue cell differentiation cell maturation cold exposure controlled study exon gene expression level gene knockdown genetic conservation high throughput sequencing human human cell in vitro study in vivo study lipid storage mouse nonhuman open reading frame RNA sequence tissue specificity white adipose tissue animal cell culture cold conserved sequence cytology genetics growth, development and aging thermogenesis tissue distribution Adipocytes, Brown Adipogenesis Adipose Tissue, Brown Animals Cell Differentiation Cells, Cultured Cold Temperature Conserved Sequence DNA-Binding Proteins Gene Knockdown Techniques Genetic Markers Humans Mice Obesity RNA, Long Noncoding Thermogenesis Tissue Distribution Transcription Factors Transcriptome
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174232
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1742322020-09-06T15:54:00Z De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis Ding C. Lim Y.C. Chia S.Y. Walet A.C.E. Xu S. Lo K.A. Zhao Y. Zhu D. Shan Z. Chen Q. Leow M.K.-S. Xu D. Sun L. DUKE-NUS MEDICAL SCHOOL long untranslated RNA long untranslated RNA dprdm16 messenger RNA short hairpin RNA transcriptome unclassified drug DNA binding protein long untranslated RNA PRDM16 protein, human transcription factor transcriptome assay correlation fat genetic marker metabolism muscle obesity protein risk assessment RNA adipogenesis adult animal cell animal experiment animal model animal tissue Article brown adipocyte brown adipose tissue cell differentiation cell maturation cold exposure controlled study exon gene expression level gene knockdown genetic conservation high throughput sequencing human human cell in vitro study in vivo study lipid storage mouse nonhuman open reading frame RNA sequence tissue specificity white adipose tissue adipogenesis animal brown adipose tissue cell culture cold conserved sequence cytology genetic marker genetics growth, development and aging metabolism obesity thermogenesis tissue distribution Adipocytes, Brown Adipogenesis Adipose Tissue, Brown Animals Cell Differentiation Cells, Cultured Cold Temperature Conserved Sequence DNA-Binding Proteins Gene Knockdown Techniques Genetic Markers Humans Mice Obesity RNA, Long Noncoding Thermogenesis Tissue Distribution Transcription Factors Transcriptome 10.1038/s41467-018-03754-3 Nature Communications 9 1 1329 2020-09-04T01:51:15Z 2020-09-04T01:51:15Z 2018 Article Ding C., Lim Y.C., Chia S.Y., Walet A.C.E., Xu S., Lo K.A., Zhao Y., Zhu D., Shan Z., Chen Q., Leow M.K.-S., Xu D., Sun L. (2018). De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis. Nature Communications 9 (1) : 1329. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-018-03754-3 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/174232 Nature Publishing Group Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
country	Singapore
collection	ScholarBank@NUS
topic	long untranslated RNA long untranslated RNA dprdm16 messenger RNA short hairpin RNA transcriptome unclassified drug DNA binding protein long untranslated RNA PRDM16 protein, human transcription factor transcriptome assay correlation fat genetic marker metabolism muscle obesity protein risk assessment RNA adipogenesis adult animal cell animal experiment animal model animal tissue Article brown adipocyte brown adipose tissue cell differentiation cell maturation cold exposure controlled study exon gene expression level gene knockdown genetic conservation high throughput sequencing human human cell in vitro study in vivo study lipid storage mouse nonhuman open reading frame RNA sequence tissue specificity white adipose tissue adipogenesis animal brown adipose tissue cell culture cold conserved sequence cytology genetic marker genetics growth, development and aging metabolism obesity thermogenesis tissue distribution Adipocytes, Brown Adipogenesis Adipose Tissue, Brown Animals Cell Differentiation Cells, Cultured Cold Temperature Conserved Sequence DNA-Binding Proteins Gene Knockdown Techniques Genetic Markers Humans Mice Obesity RNA, Long Noncoding Thermogenesis Tissue Distribution Transcription Factors Transcriptome
spellingShingle	long untranslated RNA long untranslated RNA dprdm16 messenger RNA short hairpin RNA transcriptome unclassified drug DNA binding protein long untranslated RNA PRDM16 protein, human transcription factor transcriptome assay correlation fat genetic marker metabolism muscle obesity protein risk assessment RNA adipogenesis adult animal cell animal experiment animal model animal tissue Article brown adipocyte brown adipose tissue cell differentiation cell maturation cold exposure controlled study exon gene expression level gene knockdown genetic conservation high throughput sequencing human human cell in vitro study in vivo study lipid storage mouse nonhuman open reading frame RNA sequence tissue specificity white adipose tissue adipogenesis animal brown adipose tissue cell culture cold conserved sequence cytology genetic marker genetics growth, development and aging metabolism obesity thermogenesis tissue distribution Adipocytes, Brown Adipogenesis Adipose Tissue, Brown Animals Cell Differentiation Cells, Cultured Cold Temperature Conserved Sequence DNA-Binding Proteins Gene Knockdown Techniques Genetic Markers Humans Mice Obesity RNA, Long Noncoding Thermogenesis Tissue Distribution Transcription Factors Transcriptome Ding C. Lim Y.C. Chia S.Y. Walet A.C.E. Xu S. Lo K.A. Zhao Y. Zhu D. Shan Z. Chen Q. Leow M.K.-S. Xu D. Sun L. De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis
description	10.1038/s41467-018-03754-3
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Ding C. Lim Y.C. Chia S.Y. Walet A.C.E. Xu S. Lo K.A. Zhao Y. Zhu D. Shan Z. Chen Q. Leow M.K.-S. Xu D. Sun L.
format	Article
author	Ding C. Lim Y.C. Chia S.Y. Walet A.C.E. Xu S. Lo K.A. Zhao Y. Zhu D. Shan Z. Chen Q. Leow M.K.-S. Xu D. Sun L.
author_sort	Ding C.
title	De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis
title_short	De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis
title_full	De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis
title_fullStr	De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis
title_full_unstemmed	De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis
title_sort	de novo reconstruction of human adipose transcriptome reveals conserved lncrnas as regulators of brown adipogenesis
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174232
_version_	1681101719369416704

De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis

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