Development of a multi-compartment population balance model for high-shear wet granulation with discrete element method

• المؤلفون الرئيسيون: Lee, Kok Foong, Dosta, Maksym, McGuire, Andrew D., Mosbach, Sebastian, Wagner, Wolfgang, Heinrich, Stefan, Kraft, Markus
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Stochastic Weighted Algorithm; Granulation
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/88020; http://hdl.handle.net/10220/44503

This paper presents a multi-compartment population balance model for wet granulation coupled with DEM (discrete element method) simulations. Methodologies are developed to extract relevant data from the DEM simulations to inform the population balance model. First, compartmental residence times are...