Role of the N-terminal lid in regulating the interaction of phosphorylated MDMX with p53

Role of the N-terminal lid in regulating the interaction of phosphorylated MDMX with p53

Murine double minute 4 protein (MDMX) is crucial for the regulation of the tumor suppressor protein p53. Phosphorylation of the N-terminal domain of MDMX is thought to affect its binding with the transactivation domain of p53, thus playing a role in p53 regulation. In this study, the effects of MDMX...

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Bibliographic Details
Main Authors: Chan, Jane Vin, Koh, Dawn Xin Ping, Liu, Yun, Joseph, Thomas L., Lane, David P., Verma, Chandra Shekhar, Tan, Yaw Sing
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
MDMX/MDM4
Phosphotyrosine
Online Access:https://hdl.handle.net/10356/88037
http://hdl.handle.net/10220/44520
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/88037
http://hdl.handle.net/10220/44520

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