Role of the N-terminal lid in regulating the interaction of phosphorylated MDMX with p53
Murine double minute 4 protein (MDMX) is crucial for the regulation of the tumor suppressor protein p53. Phosphorylation of the N-terminal domain of MDMX is thought to affect its binding with the transactivation domain of p53, thus playing a role in p53 regulation. In this study, the effects of MDMX...
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Main Authors: | Chan, Jane Vin, Koh, Dawn Xin Ping, Liu, Yun, Joseph, Thomas L., Lane, David P., Verma, Chandra Shekhar, Tan, Yaw Sing |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/88037 http://hdl.handle.net/10220/44520 |
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Institution: | Nanyang Technological University |
Language: | English |
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