Sequence-based multiscale modeling for high-throughput chromosome conformation capture (Hi-C) data analysis

• 主要作者: Xia, Kelin
• 其他作者: Qin, Zhaohui
• 格式: Article
• 語言: English
• 出版: 2018
• 主題: Chromosome; Data Analysis
• 在線閱讀: https://hdl.handle.net/10356/88044; http://hdl.handle.net/10220/44517
• 機構: Nanyang Technological University

In this paper, we introduce sequence-based multiscale modeling for biomolecular data analysis. We employ spectral clustering method in our modeling and reveal the difference between sequence-based global scale clustering and local scale clustering. Essentially, two types of distances, i.e., Euclidea...