Mathematical modeling and simulation of stem cell differentiation and reprogramming by Waddington's epigenetic landscape

• Main Author: Guo, Jing
• Other Authors: Zheng Jie
• Format: Theses and Dissertations
• Language: English
• Published: 2018
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences
• Online Access: https://hdl.handle.net/10356/88079; http://hdl.handle.net/10220/45611
• Institution: Nanyang Technological University

Recently, the field of computational stem cell biology, a new subdiscipline of developmental biology, has received a remarkable level of attention from the researchers. It leverages computational algorithms and tools to study the mechanisms of regulating the behaviors of embryonic stem cells (ESCs)....