Modulation of the vault protein-protein interaction for tuning of molecular release

Vaults are naturally occurring ovoid nanoparticles constructed from a protein shell that is composed of multiple copies of major vault protein (MVP). The vault-interacting domain of vault poly(ADP-ribose)-polymerase (INT) has been used as a shuttle to pack biomolecular cargo in the vault lumen. Howe...

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Bibliographic Details
Main Authors: Yu, Kang, Yau, Yin Hoe, Sinha, Ameya, Tan, Tabitha, Kickhoefer, Valerie A., Rome, Leonard H., Lee, Hwankyu, Shochat, Susana G., Lim, Sierin
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/88105
http://hdl.handle.net/10220/45629
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Institution: Nanyang Technological University
Language: English