Monocyte adhesion to atherosclerotic matrix proteins is enhanced by Asn-Gly-Arg deamidation

• Main Authors: Dutta, Bamaprasad, Park, Jung Eun, Kumar, Subodh, Hao, Piliang, Gallart-Palau, Xavier, Serra, Aida, Ren, Yan, Sorokin, Vitaly, Lee, Chuen Neng, Ho, Hee Hwa, de Kleijn, Dominique, Sze, Siu Kwan
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: DRNTU::Science::Biological sciences; Protein Deamidation; Monocyte Adhesion
• Online Access: https://hdl.handle.net/10356/88130; http://hdl.handle.net/10220/45631
• Institution: Nanyang Technological University

Atherosclerosis arises from leukocyte infiltration and thickening of the artery walls and constitutes a major component of vascular disease pathology, but the molecular events underpinning this process are not fully understood. Proteins containing an Asn-Gly-Arg (NGR) motif readily undergo deamidati...