Assembly and analysis of unmapped genome sequence reads reveal novel sequence and variation in dogs

• Main Authors: Holden, Lindsay A., Arumilli, Meharji, Hytönen, Marjo K., Hundi, Sruthi, Salojärvi, Jarkko, Brown, Kim H., Lohi, Hannes
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Canine Genome Reference (CGR); Novel Sequence; DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/88158; http://hdl.handle.net/10220/45660
• Institution: Nanyang Technological University

Dogs are excellent animal models for human disease. They have extensive veterinary histories, pedigrees, and a unique genetic system due to breeding practices. Despite these advantages, one factor limiting their usefulness is the canine genome reference (CGR) which was assembled using a single pureb...