Structural mimicry of the dengue virus envelope glycoprotein revealed by the crystallographic study of an idiotype–anti-idiotype Fab complex

Structural mimicry of the dengue virus envelope glycoprotein revealed by the crystallographic study of an idiotype–anti-idiotype Fab complex

A detailed understanding of the fine specificity of serotype-specific human antibodies is vital for the development and evaluation of new vaccines for pathogenic flaviviruses such as dengue virus (DENV) and Zika virus. In this study, we thoroughly characterize the structural footprint of an anti-idi...

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Bibliographic Details
Main Authors: Wong, Yee Hwa, Goh, Boon Chong, Lim, She Yah, Teo, En Wei, Lim, Angeline P. C., Dedon, Pete C., Hanson, Brendon J., MacAry, Paul A., Lescar, Julien
Other Authors: Jung, Jae U.
Format: Article
Language:English
Published: 2018
Subjects:
DRNTU::Science::Biological sciences
Dengue Virus
Idiotypic Antibody
Online Access:https://hdl.handle.net/10356/88847
http://hdl.handle.net/10220/45924
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/88847
http://hdl.handle.net/10220/45924

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