On-Demand Bioadhesive Dendrimers with Reduced Cytotoxicity

• Main Authors: Gao, Feng, Djordjevic, Ivan, Pokholenko, Oleksandr, Zhang, Haobo, Zhang, Junying, Steele, Terry W. J.
• 其他作者: School of Materials Science & Engineering
• 格式: Article
• 語言: English
• 出版: 2018
• 主題: Dendrimers; PAMAM
• 在線閱讀: https://hdl.handle.net/10356/89033; http://hdl.handle.net/10220/44763
• 機構: Nanyang Technological University

Tissue adhesives based on polyamidoamine (PAMAM) dendrimer, grafted with UV-sensitive aryldiazirine (PAMAM-g-diazirine) are promising new candidates for light active adhesion on soft tissues. Diazirine carbene precursors form interfacial and intermolecular covalent crosslinks with tissues after UV l...