Functional amyloids keep quorum-sensing molecules in check

• Main Authors: Seviour, Thomas, Hansen, Susan Hove, Yang, Liang, Yau, Yin Hoe, Wang, Victor Bochuan, Stenvang, Marcel R., Christiansen, Gunna, Marsili, Enrico, Givskov, Michael, Chen, Yicai, Otzen, Daniel E., Nielsen, Per Halkjær, Geifman-Shochat, Susana, Kjelleberg, Staffan, Dueholm, Morten S.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Biofilm; DRNTU::Science::Biological sciences; Amyloid
• Online Access: https://hdl.handle.net/10356/89083; http://hdl.handle.net/10220/46054
• Institution: Nanyang Technological University

The mechanism by which extracellular metabolites, including redox mediators and quorum-sensing signaling molecules, traffic through the extracellular matrix of biofilms is poorly explored. We hypothesize that functional amyloids, abundant in natural biofilms and possessing hydrophobic domains, retai...