Epigallocatechin gallate remodels overexpressed functional amyloids in Pseudomonas aeruginosa and Increases biofilm susceptibility to antibiotic treatment

Epigallocatechin gallate remodels overexpressed functional amyloids in Pseudomonas aeruginosa and Increases biofilm susceptibility to antibiotic treatment

Epigallocatechin-3-gallate (EGCG) is the major polyphenol in green tea. It has antimicrobial properties and disrupts the ordered structure of amyloid fibrils involved in human disease. The antimicrobial effect of EGCG against the opportunistic pathogen Pseudomonas aeruginosa has been shown to involv...

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Bibliographic Details
Main Authors: Stenvang, Marcel, Dueholm, Morten S., Vad, Brian S., Seviour, Thomas, Zeng, Guanghong, Geifman-Shochat, Susana, Søndergaard, Mads T., Christiansen, Gunna, Meyer, Rikke Louise, Kjelleberg, Staffan, Nielsen, Per Halkjær, Otzen, Daniel E.
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
DRNTU::Science::Biological sciences
Amyloid
Biofilm
Online Access:https://hdl.handle.net/10356/89405
http://hdl.handle.net/10220/46268
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/89405
http://hdl.handle.net/10220/46268

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