Open questions : how to get developmental biology into shape?

Open questions : how to get developmental biology into shape?

Recent technical advances have provided unprecedented insights into the selective deployment of the genome in developing organisms, but how such differential gene expression is used to sculpt the complex shapes and sizes of organs remains unclear. Here, we outline major open questions in organogenes...

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Main Authors: Saunders, Timothy E., Ingham, Philip William
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2019
Subjects:
Science::Medicine
3D Modelling
Cable-driven
Online Access:https://hdl.handle.net/10356/89199
http://hdl.handle.net/10220/49318
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Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-89199
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spelling sg-ntu-dr.10356-891992020-11-01T05:28:31Z Open questions : how to get developmental biology into shape? Saunders, Timothy E. Ingham, Philip William Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine 3D Modelling Cable-driven Recent technical advances have provided unprecedented insights into the selective deployment of the genome in developing organisms, but how such differential gene expression is used to sculpt the complex shapes and sizes of organs remains unclear. Here, we outline major open questions in organogenesis and suggest how a synthesis between developmental biology and physics can help to address them. NRF (Natl Research Foundation, S’pore) Published version 2019-07-12T03:35:13Z 2019-12-06T17:20:03Z 2019-07-12T03:35:13Z 2019-12-06T17:20:03Z 2019 Journal Article Saunders, T. E., & Ingham, P. W. (2019). Open questions : how to get developmental biology into shape?. BMC Biology, 17(1), 17-. doi:10.1186/s12915-019-0636-6 https://hdl.handle.net/10356/89199 http://hdl.handle.net/10220/49318 10.1186/s12915-019-0636-6 en BMC Biology © 2019 The Author(s). This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. 3 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Medicine
3D Modelling
Cable-driven
spellingShingle Science::Medicine
3D Modelling
Cable-driven
Saunders, Timothy E.
Ingham, Philip William
Open questions : how to get developmental biology into shape?
description Recent technical advances have provided unprecedented insights into the selective deployment of the genome in developing organisms, but how such differential gene expression is used to sculpt the complex shapes and sizes of organs remains unclear. Here, we outline major open questions in organogenesis and suggest how a synthesis between developmental biology and physics can help to address them.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Saunders, Timothy E.
Ingham, Philip William
format Article
author Saunders, Timothy E.
Ingham, Philip William
author_sort Saunders, Timothy E.
title Open questions : how to get developmental biology into shape?
title_short Open questions : how to get developmental biology into shape?
title_full Open questions : how to get developmental biology into shape?
title_fullStr Open questions : how to get developmental biology into shape?
title_full_unstemmed Open questions : how to get developmental biology into shape?
title_sort open questions : how to get developmental biology into shape?
publishDate 2019
url https://hdl.handle.net/10356/89199
http://hdl.handle.net/10220/49318
_version_ 1683494303507152896

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