Open questions : how to get developmental biology into shape?

• Main Authors: Saunders, Timothy E., Ingham, Philip William
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2019
• Subjects: Science::Medicine; 3D Modelling; Cable-driven
• Online Access: https://hdl.handle.net/10356/89199; http://hdl.handle.net/10220/49318
• Institution: Nanyang Technological University

Recent technical advances have provided unprecedented insights into the selective deployment of the genome in developing organisms, but how such differential gene expression is used to sculpt the complex shapes and sizes of organs remains unclear. Here, we outline major open questions in organogenes...