A challenging Heck reaction of maleimides
Maleimides are extremely susceptible to basic hydrolysis and gave poor yields under Heck conditions. The longstanding problem is solved with the use of a weak base KOAc in a carbonate solvent.
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sg-ntu-dr.10356-893682023-02-28T19:24:08Z A challenging Heck reaction of maleimides Lim, Li Hui Zhou, Jianrong (Steve) School of Physical and Mathematical Sciences Maleimides Heck Reaction Maleimides are extremely susceptible to basic hydrolysis and gave poor yields under Heck conditions. The longstanding problem is solved with the use of a weak base KOAc in a carbonate solvent. MOE (Min. of Education, S’pore) Accepted version 2018-05-24T04:20:48Z 2019-12-06T17:23:58Z 2018-05-24T04:20:48Z 2019-12-06T17:23:58Z 2015 Journal Article Lim, L. H., & Zhou, J. (S.) (2015). A challenging Heck reaction of maleimides. Organic Chemistry Frontiers, 2(7), 775-777. 2052-4110 https://hdl.handle.net/10356/89368 http://hdl.handle.net/10220/44888 10.1039/C5QO00015G en Organic Chemistry Frontiers © 2015 the Partner Organisations. This is the author created version of a work that has been peer reviewed and accepted for publication by Organic Chemistry Frontiers, the Partner Organisations. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1039/C5QO00015G]. 4 p. application/pdf |
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Maleimides Heck Reaction Lim, Li Hui Zhou, Jianrong (Steve) A challenging Heck reaction of maleimides |
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Maleimides are extremely susceptible to basic hydrolysis and gave poor yields under Heck conditions. The longstanding problem is solved with the use of a weak base KOAc in a carbonate solvent. |
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School of Physical and Mathematical Sciences |
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School of Physical and Mathematical Sciences Lim, Li Hui Zhou, Jianrong (Steve) |
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Article |
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Lim, Li Hui Zhou, Jianrong (Steve) |
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Lim, Li Hui |
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A challenging Heck reaction of maleimides |
title_short |
A challenging Heck reaction of maleimides |
title_full |
A challenging Heck reaction of maleimides |
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A challenging Heck reaction of maleimides |
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A challenging Heck reaction of maleimides |
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challenging heck reaction of maleimides |
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2018 |
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https://hdl.handle.net/10356/89368 http://hdl.handle.net/10220/44888 |
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