A challenging Heck reaction of maleimides

Maleimides are extremely susceptible to basic hydrolysis and gave poor yields under Heck conditions. The longstanding problem is solved with the use of a weak base KOAc in a carbonate solvent.

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Main Authors: Lim, Li Hui, Zhou, Jianrong (Steve)
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/89368
http://hdl.handle.net/10220/44888
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-893682023-02-28T19:24:08Z A challenging Heck reaction of maleimides Lim, Li Hui Zhou, Jianrong (Steve) School of Physical and Mathematical Sciences Maleimides Heck Reaction Maleimides are extremely susceptible to basic hydrolysis and gave poor yields under Heck conditions. The longstanding problem is solved with the use of a weak base KOAc in a carbonate solvent. MOE (Min. of Education, S’pore) Accepted version 2018-05-24T04:20:48Z 2019-12-06T17:23:58Z 2018-05-24T04:20:48Z 2019-12-06T17:23:58Z 2015 Journal Article Lim, L. H., & Zhou, J. (S.) (2015). A challenging Heck reaction of maleimides. Organic Chemistry Frontiers, 2(7), 775-777. 2052-4110 https://hdl.handle.net/10356/89368 http://hdl.handle.net/10220/44888 10.1039/C5QO00015G en Organic Chemistry Frontiers © 2015 the Partner Organisations. This is the author created version of a work that has been peer reviewed and accepted for publication by Organic Chemistry Frontiers, the Partner Organisations. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1039/C5QO00015G]. 4 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Maleimides
Heck Reaction
spellingShingle Maleimides
Heck Reaction
Lim, Li Hui
Zhou, Jianrong (Steve)
A challenging Heck reaction of maleimides
description Maleimides are extremely susceptible to basic hydrolysis and gave poor yields under Heck conditions. The longstanding problem is solved with the use of a weak base KOAc in a carbonate solvent.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Lim, Li Hui
Zhou, Jianrong (Steve)
format Article
author Lim, Li Hui
Zhou, Jianrong (Steve)
author_sort Lim, Li Hui
title A challenging Heck reaction of maleimides
title_short A challenging Heck reaction of maleimides
title_full A challenging Heck reaction of maleimides
title_fullStr A challenging Heck reaction of maleimides
title_full_unstemmed A challenging Heck reaction of maleimides
title_sort challenging heck reaction of maleimides
publishDate 2018
url https://hdl.handle.net/10356/89368
http://hdl.handle.net/10220/44888
_version_ 1759857175354671104