The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma

The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma

Circulating CCR2+ monocytes are crucial for maintaining the adult tissue-resident F4/80hiMHCIIhi macrophage pool in the intestinal lamina propria. Here we show that a subpopulation of CCR2-independent F4/80hiMHCIIlow macrophages, which are the most abundant F4/80hi cells in neonates, gradually decli...

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Bibliographic Details
Main Authors: Soncin, Irene, Sheng, Jianpeng, Chen, Qi, Foo, Shihui, Duan, Kaibo, Lum, Josephine, Poidinger, Michael, Zolezzi, Francesca, Karjalainen, Klaus, Ruedl, Christiane
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Online Access:https://hdl.handle.net/10356/89512
http://hdl.handle.net/10220/44929
https://doi.org/10.21979/N9/EQXCRF
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/89512
http://hdl.handle.net/10220/44929
https://doi.org/10.21979/N9/EQXCRF

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