Molecular mechanism of the Escherichia coli AhpC in the function of a chaperone under heat-shock conditions

• Main Authors: Kamariah, Neelagandan, Eisenhaber, Birgit, Eisenhaber, Frank, Grüber, Gerhard
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Heat-shock Conditions; Peroxiredoxins; DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/89689; http://hdl.handle.net/10220/46315
• Institution: Nanyang Technological University

Peroxiredoxins (Prxs) are ubiquitous antioxidants utilizing a reactive cysteine for peroxide reduction and acting as a molecular chaperone under various stress conditions. Besides other stimulating factors, oxidative- and heat stress conditions trigger their ATP-independent chaperoning function. So...