Automated fluorescence intensity and gradient analysis enables detection of rare fluorescent mutant cells deep within the tissue of RaDR mice

Automated fluorescence intensity and gradient analysis enables detection of rare fluorescent mutant cells deep within the tissue of RaDR mice

Homologous recombination (HR) events are key drivers of cancer-promoting mutations, and the ability to visualize these events in situ provides important information regarding mutant cell type, location, and clonal expansion. We have previously created the Rosa26 Direct Repeat (RaDR) mouse model wher...

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Bibliographic Details
Main Authors: Wadduwage, Dushan N., Kay, Jennifer, Singh, Vijay Raj, Kiraly, Orsolya, Sukup-Jackson, Michelle R., Rajapakse, Jagath, Engelward, Bevin P., So, Peter T. C.
Other Authors: School of Computer Science and Engineering
Format: Article
Language:English
Published: 2018
Subjects:
Homologous Recombination
Fluorescent Mutant Cells
DRNTU::Engineering::Computer science and engineering
Online Access:https://hdl.handle.net/10356/89695
http://hdl.handle.net/10220/46313
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Institution: Nanyang Technological University
Language: English

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https://hdl.handle.net/10356/89695
http://hdl.handle.net/10220/46313

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