Design and fabrication of micro-coils for NMR micro probes
The miniaturization of probes for Magnetic Resonance (MR) analytical methods-Nuclear Magnetic Resonance (NMR), Magnetic Resonance Imaging (MRI), or relaxometry- has been the latest trend which allows portability and analysis of the chemical composition of minute (in the range of nL to L) volumes...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2018
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| Online Access: | https://hdl.handle.net/10356/89765 http://hdl.handle.net/10220/46397 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | The miniaturization of probes for Magnetic Resonance (MR) analytical methods-Nuclear Magnetic Resonance (NMR), Magnetic Resonance Imaging (MRI), or
relaxometry- has been the latest trend which allows portability and analysis of
the chemical composition of minute (in the range of nL to L) volumes of sample.
MR analyses typically require that such a probe is used in an external setup with
a very strong constant magnetic field with no temporal variation and external
detector circuits. A critical aspect of the success of such an experiment is to
ensure a high signal-to-noise ratio (SNR). However, the resulting value of the
SNR delivered by a miniature probe has a complicated dependence on both the
external measurement setup, the chemical composition of the sample and the probe
design. For probe designers, there are no clear guidelines to suggest how a given
the probe will behave under any external measurement setup or chemical composition
of the sample under test, or how to approach a probe design so as to optimize
design parameters for a good performance in terms of SNR in an MR analysis, e.g.
an NMR experiment. |
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