Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast

• Main Authors: Miao, Yansong, Han, Xuemei, Zheng, Liangzhen, Xie, Ying, Mu, Yuguang, Yates, John R., Drubin, David G.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Actin; Cell Division
• Online Access: https://hdl.handle.net/10356/89797; http://hdl.handle.net/10220/47163
• Institution: Nanyang Technological University

Actin cables, composed of actin filament bundles nucleated by formins, mediate intracellular transport for cell polarity establishment and maintenance. We previously observed that metaphase cells preferentially promote actin cable assembly through cyclin-dependent kinase 1 (Cdk1) activity. However,...