Role of RhoA/Rho kinase signaling pathway in microgroove induced stem cell myogenic differentiation

• Main Authors: Li, Huaqiong, Wen, Feng, Wang, Xincai, Tan, Lay Poh
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Cell Differentiation; Rho-associated Kinases; DRNTU::Engineering::Materials
• Online Access: https://hdl.handle.net/10356/89985; http://hdl.handle.net/10220/46452
• Institution: Nanyang Technological University

In our previous report, the authors have demonstrated that direct laser machined microchannels would trigger upregulation of myogenic markers in human mesenchymal stem cells (hMSCs) through promotion of cell elongation. However, the molecular basis signaling pathways behind this observation remains...