Key players and individualists of cyclic-di-gmp signaling in burkholderia cenocepacia

• Main Authors: Richter, Anja M., Fazli, Mustafa, Schmid, Nadine, Shilling, Rebecca, Suppiger, Angela, Givskov, Michael, Eberl, Leo, Tolker-Nielsen, Tim
• 其他作者: Singapore Centre for Environmental Life Sciences and Engineering
• 格式: Article
• 語言: English
• 出版: 2019
• 主題: Burkholderia Cenocepacia; DRNTU::Science::General; Cyclic-di-GMP
• 在線閱讀: https://hdl.handle.net/10356/90251; http://hdl.handle.net/10220/48464
• 機構: Nanyang Technological University

Burkholderia cenocepacia H111 is an opportunistic pathogen associated with chronic lung infections in cystic fibrosis patients. Biofilm formation, motility and virulence of B. cenocepacia are regulated by the second messenger cyclic di-guanosine monophosphate (c-di-GMP). In the present study, we ana...