The role of membrane curvature in nanoscale topography-induced intracellular signaling

• Main Authors: Lou, Hsin-Ya, Zhao, Wenting, Zeng, Yongpeng, Cui, Bianxiao
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Nanostructures; Plasma Membrane; DRNTU::Engineering::Chemical engineering
• Online Access: https://hdl.handle.net/10356/90260; http://hdl.handle.net/10220/48454
• Institution: Nanyang Technological University

Over the past decade, there has been growing interest in developing biosensors and devices with nanoscale and vertical topography. Vertical nanostructures induce spontaneous cell engulfment, which enhances the cell–probe coupling efficiency and the sensitivity of biosensors. Although local membranes...