Preproinsulin designer antigens excluded from endoplasmic reticulum suppressed diabetes development in nod mice by dna vaccination

Preproinsulin designer antigens excluded from endoplasmic reticulum suppressed diabetes development in nod mice by dna vaccination

DNA vaccines against autoimmune type 1 diabetes (T1D) contain a nonpredictable risk to induce autoreactive T cell responses rather than a protective immunity. Little is known if (and how) antigen expression and processing requirements favor the induction of autoreactive or protective immune response...

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Bibliographic Details
Main Authors: Stifter, Katja, Schuster, Cornelia, Krieger, Jana, Spyrantis, Andreas, Boehm, Bernhard Otto, Schirmbeck, Reinhold
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2019
Subjects:
Mouse Models
Type 1 Diabetes
DRNTU::Science::Medicine
Online Access:https://hdl.handle.net/10356/90285
http://hdl.handle.net/10220/48490
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/90285
http://hdl.handle.net/10220/48490

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