MINDY1 is a downstream target of the polyamines and promotes embryonic stem cell self‐renewal

• Main Authors: Nazreen Abdul Muthalif, Vardy, Leah Anne, James, Christina, Zhao, Tian Yun, Rahim, Anisa, Saxena, Parul, Uemura, Takeshi, Tsuneyoshi, Norihiro, Ong, Sheena, Igarashi, Kazuei, Lim, Chin Yan, Dunn, Norris Ray
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: Polyamines; Embryonic Stem Cells; Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/90339; http://hdl.handle.net/10220/49909
• Institution: Nanyang Technological University

Embryonic stem cells have the ability to self‐renew or differentiate and these processes are under tight control. We previously reported that the polyamine regulator AMD1 is critical for embryonic stem cell self‐renewal. The polyamines putrescine, spermidine, and spermine are essential organic catio...