Rapid EC50 determination of hydrophobic toxicants in continuous droplet biomicrofluidics

• Main Authors: Ortiz, Raphael, Stuckey, David C., Steele, Terry W. J.
• 其他作者: School of Materials Science & Engineering
• 格式: Article
• 語言: English
• 出版: 2019
• 主題: Droplet; Engineering::Materials; Microfluidic
• 在線閱讀: https://hdl.handle.net/10356/91261; http://hdl.handle.net/10220/49445
• 機構: Nanyang Technological University

Droplet-based bioassays are attractive for increasing throughput while minimizing reagent consumption. However, the choice of continuous oil phase within the bioassay can substantially alter assay outcomes when hydrophobic reagents and analytes dynamically partition between the oil and aqueous phase...