Micro check valves for integration into polymeric microfluidic devices

In this paper we describe the design, simulation, fabrication and characterization of micro check valves suitable for integration into polymeric microfluidic devices such as micropumps or test cartridges for biomedical analysis. The valves are fabricated by a polymeric surface micromachining process...

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Main Authors: Wong, Kok-Keong, Ho, Soon-Seng, Low, Cassandra Lee-Ngo, Nguyen, Nam-Trung, Truong, Thai-Quang
Other Authors: School of Mechanical and Aerospace Engineering
Format: Article
Language:English
Published: 2012
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Online Access:https://hdl.handle.net/10356/93880
http://hdl.handle.net/10220/7864
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-938802023-03-04T17:16:28Z Micro check valves for integration into polymeric microfluidic devices Wong, Kok-Keong Ho, Soon-Seng Low, Cassandra Lee-Ngo Nguyen, Nam-Trung Truong, Thai-Quang School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering In this paper we describe the design, simulation, fabrication and characterization of micro check valves suitable for integration into polymeric microfluidic devices such as micropumps or test cartridges for biomedical analysis. The valves are fabricated by a polymeric surface micromachining process, which utilizes SU-8 as the functional material. The devices are assembled with the lamination technique. A micro check valve consists of three layers: an inlet layer, a valve layer and an outlet layer. The valve is a disc with a diameter of 1 mm. The disc is suspended on folded beams, which act as valve springs. Both valve disc and springs are fabricated in a 100 µm SU-8 layer. The valves prove a clear flow rectification function. Relatively low pressure is required for opening the valve. The valves were tested and characterized with water. One of the valves is successfully integrated into a polymeric micropump. These valves prove the facile and reliable lamination technology for the fabrication of complex polymeric microfluidic devices for biomedical analysis. Accepted version 2012-05-11T06:14:04Z 2019-12-06T18:47:03Z 2012-05-11T06:14:04Z 2019-12-06T18:47:03Z 2004 2004 Journal Article Nguyen, N. T., Truong, T. Q., Wong, K. K., Ho, S. S., & Low, C. L. N. (2004). Micro check valves for integration into polymeric microfluidic devices. Journal of Micromechanics and Microengineering, 14(1), 69–75. https://hdl.handle.net/10356/93880 http://hdl.handle.net/10220/7864 10.1088/0960-1317/14/1/309 85834 en Journal of micromechanics and microengineering © 2004 IOP Publishing Ltd. This is the author created version of a work that has been peer reviewed and accepted for publication by Journal of Micromechanics and Microengineering, IOP Publishing Ltd. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org.ezlibproxy1.ntu.edu.sg/10.1088/0960-1317/14/1/309]. 13 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Mechanical engineering
spellingShingle DRNTU::Engineering::Mechanical engineering
Wong, Kok-Keong
Ho, Soon-Seng
Low, Cassandra Lee-Ngo
Nguyen, Nam-Trung
Truong, Thai-Quang
Micro check valves for integration into polymeric microfluidic devices
description In this paper we describe the design, simulation, fabrication and characterization of micro check valves suitable for integration into polymeric microfluidic devices such as micropumps or test cartridges for biomedical analysis. The valves are fabricated by a polymeric surface micromachining process, which utilizes SU-8 as the functional material. The devices are assembled with the lamination technique. A micro check valve consists of three layers: an inlet layer, a valve layer and an outlet layer. The valve is a disc with a diameter of 1 mm. The disc is suspended on folded beams, which act as valve springs. Both valve disc and springs are fabricated in a 100 µm SU-8 layer. The valves prove a clear flow rectification function. Relatively low pressure is required for opening the valve. The valves were tested and characterized with water. One of the valves is successfully integrated into a polymeric micropump. These valves prove the facile and reliable lamination technology for the fabrication of complex polymeric microfluidic devices for biomedical analysis.
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Wong, Kok-Keong
Ho, Soon-Seng
Low, Cassandra Lee-Ngo
Nguyen, Nam-Trung
Truong, Thai-Quang
format Article
author Wong, Kok-Keong
Ho, Soon-Seng
Low, Cassandra Lee-Ngo
Nguyen, Nam-Trung
Truong, Thai-Quang
author_sort Wong, Kok-Keong
title Micro check valves for integration into polymeric microfluidic devices
title_short Micro check valves for integration into polymeric microfluidic devices
title_full Micro check valves for integration into polymeric microfluidic devices
title_fullStr Micro check valves for integration into polymeric microfluidic devices
title_full_unstemmed Micro check valves for integration into polymeric microfluidic devices
title_sort micro check valves for integration into polymeric microfluidic devices
publishDate 2012
url https://hdl.handle.net/10356/93880
http://hdl.handle.net/10220/7864
_version_ 1759856362771185664