Immobilization of recombinant vault nanoparticles on solid substrates

• Main Authors: Xia, Yun, Ramgopal, Yamini, Li, Hai, Shang, Lei, Srinivas, Parisa, Kickhoefer, Valerie A., Rome, Leonard H., Preiser, Peter Rainer, Boey, Freddy Yin Chiang, Zhang, Hua, Venkatraman, Subbu S.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Engineering::Materials
• Online Access: https://hdl.handle.net/10356/93974; http://hdl.handle.net/10220/8608
• Institution: Nanyang Technological University

Native vaults are nanoscale particles found abundantly in the cytoplasm of most eukaryotic cells. They have a capsule-like structure with a thin shell surrounding a “hollow” interior compartment. Recombinant vault particles were found to self-assemble following expression of the major vault protein...