Double spiral detection channel for on-chip chemiluminescence detection
In this paper, we introduced a three-layered microchip that consists of a double spiral channel design for chemiluminescence (CL) detection and a passive micromixer to facilitate the mixing of reagents. The design with two overlapping spiral channels doubled the CL intensity emitted from the reactio...
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sg-ntu-dr.10356-940182023-03-04T17:17:56Z Double spiral detection channel for on-chip chemiluminescence detection Lok, Khoi Seng Kwok, Yien Chian Nguyen, Nam-Trung School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering In this paper, we introduced a three-layered microchip that consists of a double spiral channel design for chemiluminescence (CL) detection and a passive micromixer to facilitate the mixing of reagents. The design with two overlapping spiral channels doubled the CL intensity emitted from the reaction as compared to the design with a single spiral channel. The addition of the passive micromixer improved the signal by 1.5 times. Luminol-based chemiluminescence reaction was used for the characterization of the device. This microchip was successfully tested with the determination of L-cysteine and uric acid. Accepted version 2012-07-31T03:41:32Z 2019-12-06T18:49:20Z 2012-07-31T03:41:32Z 2019-12-06T18:49:20Z 2012 2012 Journal Article Lok, K. S., Kwok, Y. C., & Nguyen, N. T. (2012). Double spiral detection channel for on-chip chemiluminescence detection. Sensors and Actuators B: Chemical, 169, 144-150. https://hdl.handle.net/10356/94018 http://hdl.handle.net/10220/8356 10.1016/j.snb.2012.04.047 167503 en Sensors and actuators B: chemical © 2012 Elsevier B.V. This is the author created version of a work that has been peer reviewed and accepted for publication by Sensors and Actuators B: Chemical, Elsevier B.V. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [DOI: http://dx.doi.org/10.1016/j.snb.2012.04.047]. application/pdf |
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DRNTU::Engineering::Mechanical engineering Lok, Khoi Seng Kwok, Yien Chian Nguyen, Nam-Trung Double spiral detection channel for on-chip chemiluminescence detection |
| description |
In this paper, we introduced a three-layered microchip that consists of a double spiral channel design for chemiluminescence (CL) detection and a passive micromixer to facilitate the mixing of reagents. The design with two overlapping spiral channels doubled the CL intensity emitted from the reaction as compared to the design with a single spiral channel. The addition of the passive micromixer improved the signal by 1.5 times. Luminol-based chemiluminescence reaction was used for the characterization of the device. This microchip was successfully tested with the determination of L-cysteine and uric acid. |
| author2 |
School of Mechanical and Aerospace Engineering |
| author_facet |
School of Mechanical and Aerospace Engineering Lok, Khoi Seng Kwok, Yien Chian Nguyen, Nam-Trung |
| format |
Article |
| author |
Lok, Khoi Seng Kwok, Yien Chian Nguyen, Nam-Trung |
| author_sort |
Lok, Khoi Seng |
| title |
Double spiral detection channel for on-chip chemiluminescence detection |
| title_short |
Double spiral detection channel for on-chip chemiluminescence detection |
| title_full |
Double spiral detection channel for on-chip chemiluminescence detection |
| title_fullStr |
Double spiral detection channel for on-chip chemiluminescence detection |
| title_full_unstemmed |
Double spiral detection channel for on-chip chemiluminescence detection |
| title_sort |
double spiral detection channel for on-chip chemiluminescence detection |
| publishDate |
2012 |
| url |
https://hdl.handle.net/10356/94018 http://hdl.handle.net/10220/8356 |
| _version_ |
1759856309505622016 |