Rapid determination of vitamin B12 concentration with a chemiluminescence lab on a chip

• Main Authors: Lok, Khoi Seng, Siti Zubaidah Abdul Muttalib, Lee, Peter Peng Foo, Kwok, Yien Chian, Nguyen, Nam-Trung
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Engineering::Mechanical engineering
• Online Access: https://hdl.handle.net/10356/94203; http://hdl.handle.net/10220/7933
• Institution: Nanyang Technological University

This paper reports a novel method for the rapid determination of vitamin B12 concentration in a continuous-flow lab-on-a-chip system. This new method is based on luminol-peroxide chemiluminescence (CL) assays for the detection of cobalt(II) ions in vitamin B12 molecules. The lab-on-a-chip device con...